JWH-018 binds to each the CB1 and CB2 receptors. The results of JWH-018 are largely attributable to the binding and activation of CB1 receptors. In follow, the compound suppresses the discharge of neurotransmitters inside the central anxious process, which points out the large number of results. Spice substances generally comprise other Energetic ingredients leaving the precise mechanism of action of JWH-018 unclear for the time being.
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